Salinomycin sodium ( Sodium salinomycin )

Catalog No. M15024 CAS No. 55721-31-8

A polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Salinomycin sodium
Note

Research use only, not for human use.
Brief Description

A polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration.
Description

A polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration; inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells; induces ER stressmediated autophagy and apoptosis through generation of ROS in human glioma U87MG cells.
Synonyms

Sodium salinomycin
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

Infection
Indication

——

Chemical Information

CAS Number

55721-31-8
Formula Weight

772.98
Molecular Formula

C42H69NaO11
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 15 mg/mL
SMILES

CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)[O-].[Na+]
Chemical Name

Salinomycin, sodium salt (1:1)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Mitani M, et al. Antimicrob Agents Chemother. 1976 Apr;9(4):655-60.
2. Lu D, et al. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7.
3. Yu SN, et al. Oncol Rep. 2017 Jun;37(6):3321-3328.

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